New drug to stop ‘Ozempic butt’ muscle loss side effect of obesity jabs

Posted: 10th June 2026

Source: New drug to stop ‘Ozempic butt’ muscle loss side effect of obesity jabs – BBC News

A new drug called apitegromab could help people on obesity jabs avoid unwanted muscle decline that’s been linked to flat bums or “Ozempic butt”, according to research in Nature Medicine journal., external

Around a third of the weight loss from GLP-1 obesity jabs like Wegovy and Mounjaro can come from muscle rather than fat, the US research suggests.

But in the trial with 102 adults, mostly women, those who took apitegromab with their obesity medication maintained more muscle while still losing fat, body scans showed.

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